By Frederick W. Alt
Advances in Immunology, a customary and hugely revered e-book, provides present advancements in addition to finished stories in immunology. Articles tackle the wide variety of themes that contain immunology, together with molecular and mobile activation mechanisms, phylogeny and molecular evolution, and medical modalities. Edited and authored through the most important scientists within the box, every one quantity presents updated details and instructions for the future.
* Contributions from top gurus * Informs and updates on all of the most modern advancements within the box
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Immune responses outcome from the activation of an problematic community of interacting cells taking place in particular microenvironments. awareness lately has been focussed intensively on a few matters. incorporated between those are: the developmental pathways of the 2 significant different types of lymphocytes, T and B cells; the character in their particular receptors for antigen and in their a variety of accent floor molecules; the next destiny of the cells following stumble upon with antigen offered as such or on quite a few cells; and the functionality of the effector molecules produced after winning activation via antigen.
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Extra info for Advances in Immunology, Volume 121
Journal of Biological Chemistry, 286, 6449–6457. , & Banchereau, J. (1998). Interleukin-4 and interleukin-13: Their similarities and discrepancies. International Reviews of Immunology, 17, 1–52. Constantinescu, S. , & Lodish, H. F. (1999). The erythropoietin receptor: Structure, activation and intracellular signal transduction. Trends in Endocrinology and Metabolism, 10, 18–23. Constantinescu, S. , Huang, L. , & Lodish, H. F. (2001). The erythropoietin receptor cytosolic juxtamembrane domain contains an essential, precisely oriented, hydrophobic motif.
F. (1989). A novel family of growth factor receptors: A common binding domain in the growth hormone, prolactin, erythropoietin and IL-6 receptors, and the p75 IL-2 receptor beta-chain. Biochemical and Biophysical Research Communications, 164, 788–795. Bazan, J. F. (1990). Haemopoietic receptors and helical cytokines. Immunology Today, 11, 350–354. , et al. (2010). Covering a broad dynamic range: Information processing at the erythropoietin receptor. Science, 328, 1404–1408. , Ullmann, G. , Smith, J.
Nolan, G. P. (2006). Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profiling. Nature Methods, 3, 361–368. Kubatzky, K. , Watowich, S. , et al. (2001). Self assembly of the transmembrane domain promotes signal transduction through the erythropoietin receptor. Current Biology, 11, 110–115. 34 Ignacio Moraga et al. Kumar, K. , Krolewski, J. , & Fuchs, S. Y. (2004). Phosphorylation and specific ubiquitin acceptor sites are required for ubiquitination and degradation of the IFNAR1 subunit of type I interferon receptor.
Advances in Immunology, Volume 121 by Frederick W. Alt